Boehringer Ingelheim expands animal health portfolio in India market with two new drugs launches

Boehringer Ingelheim announced the launch of two new products in their animal healthcare portfolio for the India market. The two products – NexGard and Broadline provide comprehensive parasite treatment for dogs and cats, respectively.

As the oral ectoparasiticide for dogs, NexGard treats ectoparasites. “NexGard’s novel molecule afoxolaner acts rapidly, inducing hyperexcitation and the death of ticks, fleas and mites. It starts to kill fleas before they lay eggs, thus preventing subsequent infestation. In laboratory studies, NexGard showed 100 per cent effectiveness against adult fleas 24 hours post infestation for 35 days and demonstrated greater than 90 per cent effectiveness against ticks, 48 hours post infestation for 30 days. Available only on prescription, a single chew prevents and treats parasite infestations in dogs for a full month. The high palatability of NexGard simplifies administration in dogs as well as puppies, from as early as eight weeks old and two kilograms. NexGard is also safe to be administered in the case of glycoprotein-deficient collies,” informed the company through a statement.

It also informed, “For cats and kittens, Broadline is a formulation offering both systemic and topical modes of action to target all major parasites. A single application treats all major parasitic worms in cats, including zootonic tapeworms and harmful non-diagnosable migrating larval stages of nematodes. It is safe and well-tolerated in both cats and kittens from seven weeks. In adult cats, Broadline can be used during pregnancy and lactation too. The spectrum covered in Broadline for endoparasiticides is the highest in the current options available for cats. Broadline ensures accurate and stress-free treatment for both cat and owners, encouraging compliance.”

“Given the rapid growth of pet population, it is crucial for pet owners to be aware of and administer regular parasite control for their pets. Flea infestations can quickly get out of control because they lay eggs in exponentially large numbers. Fleas are also responsible for transmitting the dog tapeworm, Dipylidium Caninum, to dogs, cats and even humans. On the other hand, ticks can cause serious disease, including Lyme disease, paralysis and anaemia. With NexGard and Broadline, we are confident that our innovative solution will help pet owners and veterinarians to protect the health of our four-legged friends in a more consistent and convenient way,” said Dr Sandeep Karkhanis, Head of Animal Health, Boehringer Ingelheim India.

Reportedly, until now, veterinarians have had to recommend a combination of products to get the same results that NexGard and Broadline can accomplish; or make a choice between which parasite represents the greatest risk and treat accordingly.

“While the pet-care industry is still at a nascent stage in India, the mindsets and attitude towards owning pets are going through a colossal shift. India pet care market is expected to grow with a CAGR of more than 20 per cent by FY 2021-22. The Indian animal healthcare market is an integral part of Boehringer Ingelheim India’s growth plans and the companion health segment is going to be one of the major growth drivers for us. The launch of these two products is another step towards strengthening our foothold in this segment,” said Sharad Tyagi, MD, Boehringer Ingelheim India.

Visit: https://veterinary-conferences.pencis.com/

Abstract Submission - https://x-i.me/ajiver1

Award Nomination - https://x-i.me/nomvera11

Member Nomination - https://x-i.me/vertmem12

#animalcare #animals #animallovers #petcare #animal #dogsofinstagram #dogs #pets #dog #veterinarian #animalwelfare #animallover #adoptdontshop #wildlife #love #animalhealth #nature #petsofinstagram #animalsofinstagram #pet #veterinary #vet #loveanimals #cute #animallove #animalrescue #veterinarymedicine #zoo #animalrights #cats

Feline Coronavirus (FCoV) and Feline Infectious Peritonitis (FIP)

What is feline infectious peritonitis?

Feline infectious peritonitis, or FIP, is a feline coronavirus variant that can be deadly to cats. It occurs when feline coronavirus (FCoV), commonly found in the feline gastrointestinal tract of cats, undergoes genetic mutations that alter its specificity from affecting intestinal cells to impacting cells of the immune system. The virus then spreads through the cat’s body, causing systemic inflammation.

Feline coronavirus and FIP are found worldwide in domestic and wild cats. Whereas 50-90% of cats test positive for FCoV-specific antibodies, less than 5% of FCoV-infected cats develop FIP. A consistent mutation in FCoV that leads to FIP has not been identified. Rather, FIP develops sporadically within each individual cat that becomes affected. A number of factors likely play roles in the development of FIP, including viral genetics, dosage, and virulence, as well as host immunity, age, breed predisposition, stress, and environmental factors.

Since some cat breeds appear to be more susceptible, a genetic component to susceptibility has been suggested, with inbreeding being a risk factor for disease development. Males also appear to be more prone to FIP than females. FIP is usually diagnosed in cats younger than three years-of-age, although cats of any age can develop the disease.

Feline infectious peritonitis generally presents in two forms, wet (effusive) and dry (non-effusive), based on the immune system response. In the wet form, fluid is produced in the abdomen and/or chest. Wet FIP reportedly accounts for approximately 80% of cases and is more common in young cats. Inflammation in organs affected by the dry form does not produce excess fluids. In some cases, affected cats can show signs of both forms.

The most common route of FCoV infection is fecal-oral transmission. It is a significant problem in households with multiple cats, with shared litter boxes being a primary source of transmission.

What are the clinical signs of feline infectious peritonitis?

Clinical signs of FIP vary depending on which organs are involved. Regardless of which form of FIP is present, the most common clinical signs are lethargy, fever, enlarged lymph nodes, inappetence, weight loss, and a deteriorating hair coat. Cats affected with the wet form of FIP can exhibit a swollen abdomen, or difficulty breathing, depending on whether fluid has accumulated in the abdomen or chest, respectively. Cats with the dry form can show a variety of clinical signs, depending on which organ(s) are involved. Approximately 5-10% of FIP cases with the dry form include neurologic signs such as ataxia, involuntary movement of the eyes (nystagmus), and seizures. Ocular signs such as uveitis can also occur in cats with FIP.

How is feline infectious peritonitis diagnosed?

Diagnosing FIP can be challenging. Patient history, clinical signs, levels of FCoV antibodies, PCR to look for FCoV genetic material, or special stains to look for viral antigen may be used for FIP diagnosis. Diagnostic imaging, including X-rays, ultrasound, or MRI may be performed depending on the site of infection.

Cats affected with FIP often exhibit high protein levels in the blood due to increased globulins, proteins that have important roles in immune function. In particular, the albumin to globulin ratio is used to distinguish FIP from other diseases. If the blood serum albumin to globulin ratio is less than 0.8, there is an increased chance that the cat has FIP; however, this is not seen in all cats with FIP.

Protein and cell counts in abdominal or thoracic fluid may also be used for FIP diagnosis. Fluid with high protein and low cell counts are consistent with wet FIP.

It is important to note that changes to the albumin to globulin ratio, as well as positive Rivalta tests can occur with other diseases as well, so they should be used in context with other information and not as sole indicators of FIP.

Visit: https://veterinary-conferences.pencis.com/

#feline #cats #cat #catsofinstagram #of #catstagram #meow #kitty #instacat #catlover #catlife #kitten #catlovers #instagram #cute #pet #catoftheday #kittens #animals #animal #pets #kittycat #felinefriends #petsofinstagram #kittensofinstagram #love #world #art #adoptdontshop #gato

Lassie

Lassie is a fictional female Rough Collie dog and is featured in a short story by Eric Knight that was later expanded to a full-length novel called Lassie Come-Home. Knight's portrayal of Lassie bears some features in common with another fictional female collie of the same name, featured in the British writer Elizabeth Gaskell's 1859 short story "The Half Brothers". In "The Half Brothers", Lassie is loved only by her young master and guides the adults back to where two boys are lost in a snowstorm.

Published in 1940, Knight's novel was filmed by Metro-Goldwyn-Mayer in 1943 as Lassie Come Home, with a dog named Pal playing Lassie. Pal then appeared with the stage name "Lassie" in six other MGM feature films through 1951. Pal's owner and trainer, Rudd Weatherwax, then acquired the Lassie name and trademark from MGM and appeared with Pal (as "Lassie") at rodeos, fairs, and similar events across America in the early 1950s. In 1954, the long-running Emmy-winning television series Lassie debuted and, over the next 19 years, a succession of Pal's descendants appeared on the series. The "Lassie" character has appeared in radio, television, film, toys, comic books, animated series, juvenile novels, and other media. Pal's descendants continue to play Lassie today.

Elizabeth Gaskell short story

An early depiction of Lassie is found in British writer Elizabeth Gaskell's 1859 short story "The Half-brothers". In the story, Lassie is described as a female collie with "intelligent, apprehensive eyes" who rescues two half-brothers who are lost and dying in the snow. When the younger brother can no longer carry on, elder brother Gregory, Lassie's master, ties a handkerchief around Lassie's neck and sends her home. Lassie arrives home, and leads the search party to the boys. When they arrive Gregory is dead, but his younger half-brother is saved. Thus, Gaskell apparently originated the character Lassie and, at the same time, defined the "Lassie saves the day" storyline that is the essence of subsequent Lassie tales.

World War I incident

According to writer Nigel Clarke in the "Shipwreck Guide to Dorset and South Devon", the original Lassie that inspired so many films and television episodes was a rough-haired crossbreed who saved the life of a sailor during World War I.

Half collie, Lassie was owned by the landlord of the Pilot Boat, a pub in the port of Lyme Regis. On New Year's Day in 1915 the Royal Navy battleship Formidable was torpedoed by a German submarine off Start Point in South Devon, with the loss of more than 500 men. In a storm that followed the accident, a life raft containing bodies was blown along the coast to Lyme Regis. In helping to deal with the crisis, the local pub in Lyme Regis, called the Pilot Boat, offered its cellar as a mortuary.

When the bodies had been laid out on the stone floor, Lassie, a crossbred collie owned by the pub owner, found her way down amongst the bodies, and she began to lick the face of one of the victims, Able Seaman John Cowan. She stayed beside him for more than half an hour, nuzzling him and keeping him warm with her fur. To everyone's astonishment, Cowan eventually stirred. He was taken to hospital and went on to make a full recovery. He visited Lassie again when he returned to thank all who saved his life.

When the officers heard the story of Lassie and what she did to rescue Cowan, they told it again and again to any reporter who would listen as it was inspirational and heart-warming. Hollywood got hold of the story, and so a star was born.

Visit: https://veterinary-conferences.pencis.com/

#lassi #foodie #food #indianfood #foodphotography #foodblogger #foodporn #mangolassi #yummy #foodstagram #milk #instafood #delicious #lassilover #sweetlassi #foodlover #curd #mango #foodgasm #icecream #buttermilk #foodiesofinstagram #drinks #india #streetfood #summer #homemade #paneer #lassishop #instagood

 Cairn Terrier

The Cairn Terrier is a terrier breed originating in the Scottish Highlands and recognized as one of Scotland's earliest working dogs. The breed was given the name Cairn because the breed's function was to hunt and chase quarry between the cairns in the Scottish highlands.

Although the breed had existed long before, the name Cairn Terrier was a compromise suggestion after the breed originally was brought to official shows in the United Kingdom in 1909 under the name Short-haired Skye terriers. This name was not acceptable to The Kennel Club due to opposition from Skye Terrier breeders, and the name Cairn Terrier was suggested as an alternative.

Cairns originated in the Scottish Highlands and the Isle of Skye, initially grouped in the "Skye Terrier" class alongside the Scottish and West Highland White Terriers. In the early 1900s, the three breeds began to be bred separately.

The Kennel Club of the United Kingdom gave the Cairn Terrier a separate register in 1912; the first year of recognition, 134 were registered, and it was in that year that the breed was given Championship status.

The Cairn Terrier has a harsh weather-resistant outer coat that can be black, cream, wheaten, red, sandy, gray, or brindled in any of these colors. Pure black, black and tan, and white are not permitted by many kennel clubs. While registration of white Cairns was once permitted, after 1917, the American Kennel Club required them to be registered as West Highland White Terriers. A notable characteristic of Cairns is that brindled Cairns frequently change colour throughout their lifetimes. It is not uncommon for a brindled Cairn to become progressively more black or silver as it ages. The Cairn is double-coated, with a soft, dense undercoat and a harsh outer coat. A well-groomed Cairn has a rough-and-ready appearance, free of artifice or exaggeration. The Cairn Terrier was registered into the American Kennel Club in 1903.

Visit: https://veterinary-conferences.pencis.com/

https://www.youtube.com/channel/UCvkycyGjQDsLEBaCoeQe6Kg

#dog #dogsofinstagram #dogs #dogstagram #instadog #doglover #dogoftheday #ilovemydog #frenchbulldog #doglovers #doglife #dogsofinsta #doggy #dogs_of_instagram #doggo #lovedogs #bulldog #rescuedog #instagramdogs #dogsofig #mydog #doglove #instadogs #cutedog #dogsofinstaworld #dogslife #happydog #rescuedogsofinstagram #dogsitting #cutedogs #dogmom #englishbulldog #lovemydog #nationaldogday #dogphotography #doggie #dogsofinstgram #bulldogsofinstagram #dogscorner #ilovedogs

Rin Tin Tin

Rin Tin Tin or Rin-Tin-Tin (September 1918 – August 10, 1932) was a male German Shepherd born in Flirey, France, who became an international star in motion pictures. He was rescued from a World War I battlefield by an American soldier, Lee Duncan, who nicknamed him "Rinty". Duncan trained Rin Tin Tin and obtained silent film work for the dog. Rin Tin Tin was an immediate box-office success and went on to appear in 27 Hollywood films, gaining worldwide fame. Along with the earlier canine film star Strongheart, Rin Tin Tin was responsible for greatly increasing the popularity of German Shepherd dogs as family pets. The immense profitability of his films contributed to the success of Warner Bros. studios and helped advance the career of Darryl F. Zanuck from screenwriter to producer and studio executive.

After Rin Tin Tin died in 1932, the name was given to several related German Shepherd dogs featured in fictional stories on film, radio, and television. Rin Tin Tin Jr. appeared in some serialized films, but was not as talented as his father. Rin Tin Tin III, said to be Rin Tin Tin's grandson, but probably only distantly related, helped promote the military use of dogs during World War II. Rin Tin Tin III also appeared in a film with child actor Robert Blake in 1947.

Duncan groomed Rin Tin Tin IV for the 1950s television series The Adventures of Rin Tin Tin, but the dog performed poorly in a screen test and was replaced in the TV show by trainer Frank Barnes's dogs, primarily one named Flame Jr., called JR, with the public led to believe otherwise. Instead of shooting episodes, Rin Tin Tin IV stayed at home in Riverside, California. The TV show Rin Tin Tin was nominated for a PATSY Award in both 1958 and 1959 but did not win.

After Duncan died in 1960, the screen property of Rin Tin Tin passed to TV producer Herbert B. Leonard, who worked on further adaptations such as the 1988–1993 Canadian-made TV show Katts and Dog, which was called Rin Tin Tin: K-9 Cop in the US and Rintintin Junior in France. Following Leonard's death in 2006, his lawyer James Tierney made the 2007 children's film Finding Rin Tin Tin, an American–Bulgarian production based on Duncan's discovery of the dog in France. Meanwhile, a Rin Tin Tin memorabilia collection was being amassed by Texas resident Jannettia Propps Brodsgaard, who had purchased several direct descendant dogs from Duncan beginning with Rinty Tin Tin Brodsgaard in 1957. Brodsgaard bred the dogs to keep the bloodline. Brodsgaard's granddaughter, Daphne Hereford, continued to build on the tradition and bloodline of Rin Tin Tin from 1988 to 2011; she was the first to trademark the name Rin Tin Tin, in 1993, and she bought the domain names rintintin.com and rintintin.net to establish a website. Hereford also opened a short-lived Rin Tin Tin museum in Latexo, Texas. Hereford passed the tradition to her daughter, Dorothy Yanchak, in 2011. The current dog, Rin Tin Tin XII, owned by Yanchak, takes part in public events to represent the Rin Tin Tin legacy.

Visit: https://veterinary-conferences.pencis.com/

https://www.youtube.com/channel/UCvkycyGjQDsLEBaCoeQe6Kg

#dog #dogsofinstagram #dogs #dogstagram #instadog #doglover #dogoftheday #ilovemydog #frenchbulldog #doglovers #doglife #dogsofinsta #doggy #dogs_of_instagram #doggo #lovedogs #bulldog #rescuedog #instagramdogs #dogsofig #mydog #doglove #instadogs #cutedog #dogsofinstaworld #dogslife #happydog #rescuedogsofinstagram #dogsitting #cutedogs #dogmom #englishbulldog #lovemydog #nationaldogday #dogphotography #doggie #dogsofinstgram #bulldogsofinstagram #dogscorner #ilovedogs